Unlike the hardened, tyrant, Sandra Hope, I like to think of the materials I use as tools :) I do about 99% of coloring on the computer now. I use Adobe Photoshop almost exclusively for coloring, although I have been known to use Corel Painter every now and then to mix it up. I am a Mac freak so I will always recommend a Mac for doing graphics. There WAS a day when Photoshop was not too PC friendly, but those days are long gone.
Here's a pic of my desk and all the tools I use:
1) My Mac. I work on a DuoCore 2.3 G5 with 1.5 gigs of Ram (about a gig of that is dedicated to Photoshop). Just had to buy this puppy to work on the 6-page spread that is appearing in the next issue of All Star BnR.
2) Monitor. Looove the flat-panel! This is a 22" Cinema display.
3) Wacom tablet. I work on a 6"x8" Intuous 3 tablet. I recommend a tablet to anyone trying to do graphics on the computer--worth every penny!
4) Nostromo n52 by Belkin. It's a programmable keypad that was developed mostly for gamers, but I use it for coloring...mostly ;) This one is optional, but my rendering speed has increased since I bought it.
5) External hard drive. I keep double copies of everything I work on 'cause you never know when you're machine's gonna up and croak (knocking on wood). This one's a Lacie 250 Gig-er.
6) iSight. Think I've used this thing twice for video chats. I use it for the microphone/audio chats.
7) DVD collection. My best pal during those long nights when all that's on TV is infomercials I have already memorized and I am in-between Netflix deliveries. Currently viewing them in Alphabetical order (started the B's last night) Geek check...I win!
8) Desk. Best purchase ever. It's an Anthro Console unit. This company makes the best desks IMHO. They are customizable and expandable. Now all I need to figure out is how to fit it in the grave with me.
PS-No, drugs on desk are not speed or anything like that. Simply a pain reliever for a recent soccer injury.